Tokishakuyakusan

A new treatment proposed by Japanese researcher Masayoshi Kabayashi of Mie University Medical School at the ISOT (International Symposium on Olfaction and Taste) conference in Iceland, June 2024

Dr Masayoshi Kabayashi made a presentation in the clinical session of ISOT to describe his use of a blend of traditional Japanese medicines to treat post infectious olfactory loss. The product, Tokishakuyakusan, is a “Kampo”, or traditional mixture, that has been used to treat gynaecological disorders. Another name for it is TJ-23. The effect of the product is to reduce inflammation. 

Read the research here.

Read how it has been used for gynaecological disorders (endometriosis) here.

The recommendation is: 

2.5 g Tokishakuyakusan, three times a day 

Zinc supplement at recommended dosage daily

B12 supplement at recommended dosage daily

It is vital to use this regimen along with smell training.

What is it?  Is it a regulated product?

“Traditional Japanese medicines (Kampo) are increasingly recognized to have useful clinical applications in Japan. Tokishakuyakusan (TSS), a pharmaceutical-grade Kampo, is currently manufactured under strict quality controls and according to Japan’s good manufacturing practice (GMP). This medicine has been approved as a prescription drug by the Japanese Ministry of Health, Labour and Welfare, and has been prescribed for various gynecologic disorders (Terauchi et al., 2014). TSS is especially well known for managing dysmenorrhea (Kotani et al., 1997; Yoshino et al., 2016) in patients with endometriosis and adenomyosis (Tanaka, 2003), although its size reductive effects on these lesions have not been shown. Until today, the mechanism by which TSS reduces dysmenorrhea associated with endometriosis has not been determined.”

This quote comes from the article about gynecological problems, linked above.

In his presentation, Dr Masayoshi Kabayashi described the treatment program as “increasing nerve growth factor (NGF) in the olfactory bulb.”

Where can you get it? 

You should use google to look. The ckos Network does not recommend any particular outlet. A quick search turned up a Japanese pharmacy that would send to the UK with express shipping, but as with Glialia, the cost of the shipping was equal to the cost of the product. That was just a quick search–the first two pages of google. It is recommended to read the articles and look for a company that will deliver to you in your home country.

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